Patient safety and mortality reduction are critical priorities in Intensive Care Units (ICUs), where critically ill patients require complex and continuous monitoring. Critical care nurses are central to the delivery of safe and effective care, as their skills, vigilance, and clinical judgment directly influence patient outcomes. This study examines the role of critical care nurses in enhancing patient safety and reducing mortality in ICUs. Key responsibilities of ICU nurses include continuous patient assessment, early detection of complications, administration of high-risk medications, management of advanced medical devices, infection control, and effective interdisciplinary communication. Factors affecting nurse performance, such as staffing levels, workload, specialized training, organizational support, and work environment, significantly impact the quality of care and patient outcomes. Evidence from recent studies indicates that adequate nurse-to-patient ratios, adherence to standardized protocols, and ongoing professional development contribute to decreased adverse events and lower mortality rates. Additionally, fostering a culture of safety, leveraging technology, and promoting teamwork improve situational awareness and coordination among ICU staff. Implementing these strategies enhances clinical outcomes, increases patient satisfaction, and strengthens overall healthcare quality. This study highlights that investment in the development, well-being, and support of critical care nurses is fundamental for achieving safe, high-quality care in ICUs. In conclusion, critical care nurses remain indispensable in improving patient safety, preventing complications, and reducing mortality, ultimately contributing to the overall effectiveness and resilience of intensive care services.

Critical Care Nurses Patient Safety ICU Mortality Nurse Staffing Quality of Care